FRCA Notes


Post-Tonsillectomy Bleed


  • Haemorrhage is the most serious surgical complication of tonsillectomy and accounts for around a third of tonsillectomy-related deaths
  • Post-tonsillectomy bleeding can be classified as either:
    • Primary: within 24hrs of surgery, usually due to surgical technique; most occur within the first 4 - 6hrs
    • Secondary: from 24hrs to 28 days post-operatively, due to wound healing and sloughing of the eschar; peaks at days 5 - 7

  • In the UK National Prospective Tonsillectomy Audit, the overall haemorrhage rate was 3.5%, with 0.9% returning to theatre
  • Primary haemorrhage occurred in 0.6%; the majority of bleeds were therefore secondary
  • Primary bleeds are typically seen in the hospital recovery or ward setting, while secondary bleeds usually re-present via the emergency department

  • Post-tonsillectomy bleeding is typically a venous or capillary ooze from the tonsillar bed
Arterial supply Venous drainage
Ascending pharyngeal artery Tonsillar capsule venous plexus
Lesser & ascending palatine arteries Lingual vein
Tonsillar artery Pharyngeal venous plexus
Dorsal lingual artery
Facial artery


Surgical risk factors

  • Hot techniques (e.g. diathermy) reduce intra-operative bleeding but increase secondary bleeding from thermal injury, compared with cold dissection
  • The Cochrane bods found no robust evidence that a coblation technique increases risk of primary bleeding, although it may slightly increase secondary bleeding
  • Bleeding is more common after tonsillectomy than tonsillotomy (4.2% vs 1.5%), with higher re-operation rates (2.2% vs 0.64%)
  • An inexperienced surgeon during the initial surgery increases risk of bleeding

Patient risk factors

  • Adults bleed more than children; age >6yrs increases the rate of secondary bleeding
  • Indication: highest rates with quinsy and recurrent tonsillitis, lowest with obstructive symptoms
  • Perhaps counter-intuitively, presence of abnormal coagulation doesn't appear to increase risk
  • Obesity does not increase risk

Drugs

  • Meta-analyses have not shown an increased risk of bleeding with NSAIDs; ketorolac is the exception and should be avoided
  • Dexamethasone was once implicated, but this has not been substantiated

Airway

  • Anticipate a difficult airway on account of:
    • Blood loss obscuring laryngoscopic view
    • Risk of aspiration of swallowed blood or post-operative oral intake (full stomach)
    • Airway oedema from recent airway instrumentation/surgery

Hypovolaemia

  • Blood loss is difficult to quantify, as it occurs over several hours and is largely swallowed
  • A child spitting blood is likely to be significantly hypovolaemic and anaemic
  • Early signs: tachycardia, tachypnoea, prolonged capillary refill, reduced urine output
  • Late signs: hypotension and altered conscious level indicate advanced volume depletion

Other considerations

  • Patient has recently had a GA; possible residual anaesthetic drugs and opioids in a primary bleed
  • Potential for undiagnosed coagulation disorder
  • Patient and parental anxiety/distress

Post-tonsillectomy bleeds are an emergency and I would seek senior anaesthetic and ENT support as well as making a rapid but thorough assessment of the patient


Perioperative management of the patient with a post-tonsillectomy bleed


Resuscitation

  • An ABCDE approach and 100% oxygen first-off; sit the patient up or lean forwards to allow blood to drain
  • The patient should be managed à la major haemorrhage:
    • Wide-bore IV access; intraosseous access if required
    • Urgent bloods: group & cross-match, clotting profile, FBC, U&E, venous gas, point-of-care Hb and visco-elastic haemostatic assay
    • Prompt resuscitation with crystalloid or blood, guided by trends in monitoring
    • Consider TXA
    • Ensure normothermia
  • Induction in a hypovolaemic child can precipitate cardiovascular collapse; resuscitate and induce once haemodynamically stable

Planning

  • Review the previous anaesthetic chart: ETT size, grade of intubation, drugs given
  • Have smaller-than-expected ETTs and a selection of laryngoscope blades available
  • Two working suction devices, ideally with a dedicated assistant
  • Videolaryngoscope, extra light source and difficult airway trolley
  • Blood and blood products available in theatre
  • ENT surgeon scrubbed and present at induction

Induction

  • Two techniques are described, each with their own (de)merits:
    1. RSI with slight head-down tilt (most common)
    2. Inhalational induction in the left lateral, head-down position
  • Reported incidence of difficult intubation is ∽3%
  • Transient hypoxia is the most common complication during induction (up to 10%); gentle bagging post-induction as part of a modified RSI technique can reduce this

Rapid sequence induction

Advantages Disadvantages
Rapid control of the airway Pre-oxygenation difficult, especially in an anxious child
Reduces risk of aspiration Apnoea increases risk of hypoxaemia
NMBA optimises intubating conditions Bag-mask ventilation may inflate the stomach
Familiar technique; less stressful for the child Risk of CV collapse if under-resuscitated

Inhalational induction (lateral, head-down)

Advantages Disadvantages
Blood drains from the airway via gravity May be difficult in an anxious child
Spontaneous ventilation maintained Deep volatile anaesthesia risks CV instability in hypovolaemia
Allows ongoing oxygenation during induction Risk of aspiration and laryngospasm
Unfamiliar technique; intubation in the lateral position

  • Use reduced doses of induction agent and consider suxamethonium

Maintenance

  • Controlled ventilation provides good conditions for haemostasis
  • Continue fluid resuscitation and transfusion of blood products as necessary
  • Once haemostasis is achieved, pass a large-bore orogastric tube under direct vision and empty the stomach of blood and clots

Extubation

  • Thorough suctioning of the upper airway
  • Fully reverse neuromuscular blockade
  • Extubate wide awake, in the left lateral, head-down position

  • Close monitoring for recurrence of bleeding; at least 24hrs admission is required
  • Check Hb and coagulation post-operatively, particularly after transfusion
  • HDU care may be required after massive haemorrhage or a difficult airway
  • Consider investigation for an underlying bleeding disorder if there is no obvious surgical cause